Highways - Argonia is located on US Highway 160.

Railroad - The Burlington Northern Railroad runs through Argonia and is part of the double-tracking project from Chicago to California.

Airports - Argonia's airport supports small private air traffic and provides a landing area for emergency airlift services. There are also airports in nearby Caldwell and Wellington. Commercial air travel is available at Wichita's Mid-Continent is only 35 minutes away.